ABSTRACT
Hot water is good for throat, but the coronavirus 2019 (COVID-19) hidden behind sinuses about 3-4 days. There was no way through which the warm water would reach behind sinuses. The virus that is hiding behind the sinuses enters the lungs within 4 to 5 days and causes respiratory problems. Inhaling vapor reaches the back of the sinuses. Steam inhalation thins mucus and clears nasal passages and reduces inflammation of the upper respiratory tract or inhibits viral replication due to the heat of the steam. The virus is paralyzed at 50 ° C. The virus becomes so weak at 60 C that it can be resisted by the human immune 0 system. The virus is completely dead at 70 °C. COVID-19 can be killed by breathing vapours through the nose and mouth, according to doctors. Symptoms of mild to moderate infection (COVID-19) usually disappear through vapor inhalation. If everyone started a week-long streaming campaign, the pandemic would end soon. The deadly COVID- 19 is likely to be eliminated if everyone inhales steam during the week. There are no negative consequences to this exercise, and it is inexpensive. This review article describes the benefits of inhalation of steam and its use as an adjunct treatment during the COVID-19 pandemic
ABSTRACT
A comparative pharmacokinetic study of enrofloxacin (5 mg/kg, sc) was conducted in probenecid-pretreated (70 mg/kg, orally 1.5 h prior to enrofloxacin administration) lactating goats to assess the effect of probenecid on the kinetics of enrofloxacin. Concentration of enrofloxacin in plasma, milk and urine was estimated by microbiological assay using Escherichia coli (ATCC 25922). Minimum detection level of enrofloxacin was 0.01 microg/ml. The plasma log concentration versus time curve showed monophasic pattern and followed one compartment open model. Plasma drug concentration was significantly higher during 1-2 h in probenecid-pretreated group. Significantly higher drug concentration in milk was noted at most of the time points, while significantly lower urine drug concentration (0.083-1 h and 5-12 h) were obtained in probenecid-pretreated group. The kinetic parameters (A, B and 3) were significantly higher, while t(1/2)beta, MRT and Vd(area) were significantly lower in probenecid-pretreated group. Probenecid pretreatment decreased the urinary excretion of enrofloxacin, whereas enhanced excretion in milk which could be useful in cases of affections of udder in goats.
Subject(s)
Animals , Female , Fluoroquinolones/administration & dosage , Fluoroquinolones/analysis , Fluoroquinolones/pharmacokinetics , Goats/blood , Goats/physiology , Goats/urine , Injections, Subcutaneous , Lactation/drug effects , Milk/chemistry , Probenecid/administration & dosage , Probenecid/pharmacologyABSTRACT
The blood levels and tissue dispersion of sulfamoxole in poultry has been investigated. The clinical importance and public health hazards on the basis of the results obtained has been discussed.